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Charge Profile Analysis Reveals That Activation of Pro-apoptotic Regulators Bax and Bak Relies on Charge Transfer Mediated Allosteric Regulation

  • Crina-Maria Ionescu,

    Affiliations CEITEC - Central European Institute of Technology, Masaryk University, Brno, Czech Republic, National Centre for Biomolecular Research, Masaryk University, Brno, Czech Republic

  • Radka Svobodová Vařeková,

    Affiliations CEITEC - Central European Institute of Technology, Masaryk University, Brno, Czech Republic, National Centre for Biomolecular Research, Masaryk University, Brno, Czech Republic

  • Jochen H. M. Prehn,

    Affiliations Centre for Systems Medicine, Royal College of Surgeons in Ireland, Dublin, Ireland, Department of Physiology and Medical Physics, Royal College of Surgeons in Ireland, Dublin, Ireland

  • Heinrich J. Huber,

    Affiliations Centre for Systems Medicine, Royal College of Surgeons in Ireland, Dublin, Ireland, Department of Physiology and Medical Physics, Royal College of Surgeons in Ireland, Dublin, Ireland

  • Jaroslav Koča

    jkoca@ceitec.muni.cz

    Affiliations CEITEC - Central European Institute of Technology, Masaryk University, Brno, Czech Republic, National Centre for Biomolecular Research, Masaryk University, Brno, Czech Republic

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