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Research Article

Efficiency and Power as a Function of Sequence Coverage, SNP Array Density, and Imputation

  • Jason Flannick,

    Affiliations: Broad Institute of Harvard and MIT, Cambridge, Massachusetts, United States of America, Department of Molecular Biology and Diabetes Unit, Massachusetts General Hospital, Boston, Massachusetts, United States of America

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  • Joshua M. Korn,

    Affiliations: Broad Institute of Harvard and MIT, Cambridge, Massachusetts, United States of America, Department of Molecular Biology and Diabetes Unit, Massachusetts General Hospital, Boston, Massachusetts, United States of America, Harvard-MIT Division of Health Sciences and Technology, Cambridge, Massachusetts, United States of America, Graduate Program in Biophysics, Harvard University, Cambridge, Massachusetts, United States of America

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  • Pierre Fontanillas,

    Affiliation: Broad Institute of Harvard and MIT, Cambridge, Massachusetts, United States of America

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  • George B. Grant,

    Affiliation: Broad Institute of Harvard and MIT, Cambridge, Massachusetts, United States of America

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  • Eric Banks,

    Affiliation: Broad Institute of Harvard and MIT, Cambridge, Massachusetts, United States of America

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  • Mark A. Depristo,

    Affiliation: Broad Institute of Harvard and MIT, Cambridge, Massachusetts, United States of America

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  • David Altshuler mail

    altshuler@molbio.mgh.harvard.edu

    Affiliations: Broad Institute of Harvard and MIT, Cambridge, Massachusetts, United States of America, Department of Molecular Biology and Diabetes Unit, Massachusetts General Hospital, Boston, Massachusetts, United States of America, Department of Genetics and Medicine, Harvard Medical School, Boston, Massachusetts, United States of America

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  • Published: July 12, 2012
  • DOI: 10.1371/journal.pcbi.1002604

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