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Research Article

Asymmetric PTEN Distribution Regulated by Spatial Heterogeneity in Membrane-Binding State Transitions

  • Satomi Matsuoka,

    Affiliations: Laboratory for Cell Signaling Dynamics, RIKEN Quantitative Biology Center, Suita, Japan, Laboratories for Nanobiology, Graduate School of Frontier Biosciences, Osaka University, Suita, Japan, CREST, Japan Science and Technology Agency (JST), Suita, Japan

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  • Tatsuo Shibata,

    Affiliations: CREST, Japan Science and Technology Agency (JST), Suita, Japan, Laboratories for Physical Biology, RIKEN Center for Developmental Biology, Kobe, Japan

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  • Masahiro Ueda mail

    ueda@bio.sci.osaka-u.ac.jp

    Affiliations: Laboratory for Cell Signaling Dynamics, RIKEN Quantitative Biology Center, Suita, Japan, Laboratories for Nanobiology, Graduate School of Frontier Biosciences, Osaka University, Suita, Japan, CREST, Japan Science and Technology Agency (JST), Suita, Japan, Laboratory of Single Molecule Biology, Department of Biological Sciences, Graduate School of Science, Osaka University, Toyonaka, Japan

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  • Published: January 10, 2013
  • DOI: 10.1371/journal.pcbi.1002862

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