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Research Article

Distinct Types of Disorder in the Human Proteome: Functional Implications for Alternative Splicing

  • Recep Colak equal contributor,

    equal contributor Contributed equally to this work with: Recep Colak, TaeHyung Kim

    Affiliations: The Donnelly Centre, University of Toronto, Toronto, Ontario, Canada, Banting and Best Department of Medical Research, University of Toronto, Toronto, Ontario, Canada, Department of Computer Science, University of Toronto, Toronto, Ontario, Canada

    X
  • TaeHyung Kim equal contributor,

    equal contributor Contributed equally to this work with: Recep Colak, TaeHyung Kim

    Affiliations: The Donnelly Centre, University of Toronto, Toronto, Ontario, Canada, Banting and Best Department of Medical Research, University of Toronto, Toronto, Ontario, Canada, Department of Computer Science, University of Toronto, Toronto, Ontario, Canada

    X
  • Magali Michaut,

    Affiliations: The Donnelly Centre, University of Toronto, Toronto, Ontario, Canada, Banting and Best Department of Medical Research, University of Toronto, Toronto, Ontario, Canada

    X
  • Mark Sun,

    Affiliations: The Donnelly Centre, University of Toronto, Toronto, Ontario, Canada, Banting and Best Department of Medical Research, University of Toronto, Toronto, Ontario, Canada, Department of Computer Science, University of Toronto, Toronto, Ontario, Canada

    X
  • Manuel Irimia,

    Affiliations: The Donnelly Centre, University of Toronto, Toronto, Ontario, Canada, Banting and Best Department of Medical Research, University of Toronto, Toronto, Ontario, Canada

    X
  • Jeremy Bellay,

    Affiliation: Department of Computer Science and Engineering, University of Minnesota, Minneapolis, Minnesota, United States of America

    X
  • Chad L. Myers,

    Affiliation: Department of Computer Science and Engineering, University of Minnesota, Minneapolis, Minnesota, United States of America

    X
  • Benjamin J. Blencowe mail,

    b.blencowe@utoronto.ca (BJB); pi@kimlab.org (PMK)

    Affiliations: The Donnelly Centre, University of Toronto, Toronto, Ontario, Canada, Banting and Best Department of Medical Research, University of Toronto, Toronto, Ontario, Canada

    X
  • Philip M. Kim mail

    b.blencowe@utoronto.ca (BJB); pi@kimlab.org (PMK)

    Affiliations: The Donnelly Centre, University of Toronto, Toronto, Ontario, Canada, Banting and Best Department of Medical Research, University of Toronto, Toronto, Ontario, Canada, Department of Computer Science and Engineering, University of Minnesota, Minneapolis, Minnesota, United States of America, Department of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada

    X
  • Published: April 25, 2013
  • DOI: 10.1371/journal.pcbi.1003030

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