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Research Article

Perturbation Biology: Inferring Signaling Networks in Cellular Systems

  • Evan J. Molinelli equal contributor,

    equal contributor Contributed equally to this work with: Evan J. Molinelli, Anil Korkut, Weiqing Wang

    Affiliations: Computational Biology Program, Memorial Sloan-Kettering Cancer Center, New York, New York, United States of America, Tri-Institutional Program for Computational Biology and Medicine, Weill Cornell Medical College, New York, New York, United States of America

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  • Anil Korkut equal contributor,

    equal contributor Contributed equally to this work with: Evan J. Molinelli, Anil Korkut, Weiqing Wang

    Affiliation: Computational Biology Program, Memorial Sloan-Kettering Cancer Center, New York, New York, United States of America

    X
  • Weiqing Wang equal contributor,

    equal contributor Contributed equally to this work with: Evan J. Molinelli, Anil Korkut, Weiqing Wang

    Affiliation: Computational Biology Program, Memorial Sloan-Kettering Cancer Center, New York, New York, United States of America

    X
  • Martin L. Miller,

    Affiliation: Computational Biology Program, Memorial Sloan-Kettering Cancer Center, New York, New York, United States of America

    X
  • Nicholas P. Gauthier,

    Affiliation: Computational Biology Program, Memorial Sloan-Kettering Cancer Center, New York, New York, United States of America

    X
  • Xiaohong Jing,

    Affiliation: Computational Biology Program, Memorial Sloan-Kettering Cancer Center, New York, New York, United States of America

    X
  • Poorvi Kaushik,

    Affiliations: Computational Biology Program, Memorial Sloan-Kettering Cancer Center, New York, New York, United States of America, Tri-Institutional Program for Computational Biology and Medicine, Weill Cornell Medical College, New York, New York, United States of America

    X
  • Qin He,

    Affiliation: Computational Biology Program, Memorial Sloan-Kettering Cancer Center, New York, New York, United States of America

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  • Gordon Mills,

    Affiliation: Department of Systems Biology, The University of Texas MD Anderson Cancer Center, Houston, Texas, United States of America

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  • David B. Solit,

    Affiliations: Program in Molecular Pharmacology, Memorial Sloan-Kettering Cancer Center, New York, New York, United States of America, Human Oncology and Pathogenesis Program, Memorial Sloan-Kettering Cancer Center, New York, New York, United States of America

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  • Christine A. Pratilas,

    Affiliations: Program in Molecular Pharmacology, Memorial Sloan-Kettering Cancer Center, New York, New York, United States of America, Department of Pediatrics, Memorial Sloan-Kettering Cancer Center, New York, New York, United States of America

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  • Martin Weigt,

    Affiliation: Laboratoire de Génomique des Microorganismes, Université Pierre et Marie Curie, Paris, France

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  • Alfredo Braunstein,

    Affiliation: Politecnico di Torino and Human Genetics Foundation, HuGeF, Torino, Italy

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  • Andrea Pagnani,

    Affiliation: Politecnico di Torino and Human Genetics Foundation, HuGeF, Torino, Italy

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  • Riccardo Zecchina,

    Affiliation: Politecnico di Torino and Human Genetics Foundation, HuGeF, Torino, Italy

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  • Chris Sander mail

    perturbation-biology@cbio.mskcc.org

    Affiliation: Computational Biology Program, Memorial Sloan-Kettering Cancer Center, New York, New York, United States of America

    X
  • Published: December 19, 2013
  • DOI: 10.1371/journal.pcbi.1003290

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