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The Structural Pathway of Interleukin 1 (IL-1) Initiated Signaling Reveals Mechanisms of Oncogenic Mutations and SNPs in Inflammation and Cancer

  • Saliha Ece Acuner Ozbabacan,

    Affiliation Center for Computational Biology and Bioinformatics and College of Engineering, Koc University, Sariyer Istanbul, Turkey

  • Attila Gursoy ,

    agursoy@ku.edu.tr (AG); okeskin@ku.edu.tr (OK)

    Affiliation Center for Computational Biology and Bioinformatics and College of Engineering, Koc University, Sariyer Istanbul, Turkey

  • Ruth Nussinov,

    Affiliations Cancer and Inflammation Program, Leidos Biomedical Research, Inc., National Cancer Institute, Frederick National Laboratory, Frederick, Maryland, United States of America, Sackler Inst. of Molecular Medicine, Department of Human Genetics and Molecular Medicine, Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel

  • Ozlem Keskin

    agursoy@ku.edu.tr (AG); okeskin@ku.edu.tr (OK)

    Affiliation Center for Computational Biology and Bioinformatics and College of Engineering, Koc University, Sariyer Istanbul, Turkey

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