The Self-Limiting Dynamics of TGF-β Signaling In Silico and In Vitro, with Negative Feedback through PPM1A Upregulation

• Junjie Wang,

  Affiliations Computational and Systems Biology, Singapore-MIT Alliance, Singapore, Mechanobiology Institute, Singapore

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• Lisa Tucker-Kellogg,

  Affiliations Computational and Systems Biology, Singapore-MIT Alliance, Singapore, Mechanobiology Institute, Singapore, Centre for Computational Biology, Duke-NUS Graduate Medical School, Singapore

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• Inn Chuan Ng,

  Affiliation NUS Graduate School for Integrative Science and Engineering, National University of Singapore, Singapore

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• Ruirui Jia,

  Affiliation Department of Physiology, National University of Singapore, Singapore

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• P. S. Thiagarajan,

  Affiliations NUS Graduate School for Integrative Science and Engineering, National University of Singapore, Singapore, School of Computing, National University of Singapore, Singapore

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• Jacob K. White,

  Affiliations Computational and Systems Biology, Singapore-MIT Alliance, Singapore, Department of Electrical Engineering and Computer Science, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America

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• Hanry Yu

  * E-mail: hanry_yu@nuhs.edu.sg

  Affiliations Computational and Systems Biology, Singapore-MIT Alliance, Singapore, Mechanobiology Institute, Singapore, NUS Graduate School for Integrative Science and Engineering, National University of Singapore, Singapore, Department of Physiology, National University of Singapore, Singapore, Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America

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