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Research Article

ODE Constrained Mixture Modelling: A Method for Unraveling Subpopulation Structures and Dynamics

  • Jan Hasenauer mail,

    jan.hasenauer@helmholtz-muenchen.de

    Affiliations: Institute of Computational Biology, Helmholtz Center Munich, Munich, Germany, Division of Mathematical Modeling of Biological Systems, Department of Mathematics, University of Technology Munich, Munich, Germany

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  • Christine Hasenauer,

    Affiliation: Max Planck Institute for Molecular Genetics, Berlin, Germany

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  • Tim Hucho,

    Affiliations: Max Planck Institute for Molecular Genetics, Berlin, Germany, Division of Experimental Anesthesiology and Pain Research, Department of Anesthesiology and Intensive Care Medicine, University Hospital Cologne, Cologne, Germany

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  • Fabian J. Theis

    Affiliations: Institute of Computational Biology, Helmholtz Center Munich, Munich, Germany, Division of Mathematical Modeling of Biological Systems, Department of Mathematics, University of Technology Munich, Munich, Germany

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  • Published: July 03, 2014
  • DOI: 10.1371/journal.pcbi.1003686

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