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Co-Regulation of Metabolic Genes Is Better Explained by Flux Coupling Than by Network Distance

  • Richard A Notebaart,

    Affiliation Center for Molecular and Biomolecular Informatics (NCMLS), Radboud University Nijmegen Medical Center, Nijmegen, The Netherlands

  • Bas Teusink,

    Affiliations Center for Molecular and Biomolecular Informatics (NCMLS), Radboud University Nijmegen Medical Center, Nijmegen, The Netherlands , NIZO Food Research BV, Ede, The Netherlands , TI Food and Nutrition (WCFS), Wageningen, The Netherlands

  • Roland J Siezen,

    Affiliations Center for Molecular and Biomolecular Informatics (NCMLS), Radboud University Nijmegen Medical Center, Nijmegen, The Netherlands , NIZO Food Research BV, Ede, The Netherlands , TI Food and Nutrition (WCFS), Wageningen, The Netherlands

  • Balázs Papp

    To whom correspondence should be addressed. E-mail: pappb@brc.hu

    Affiliations Institute of Biochemistry, Biological Research Center, Szeged, Hungary , Faculty of Life Sciences, The University of Manchester, Manchester, United Kingdom

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