Inversion of the Balance between Hydrophobic and Hydrogen Bonding Interactions in Protein Folding and Aggregation

Open Access

Peer-reviewed

Research Article

Anthony W. Fitzpatrick,

Affiliation Department of Chemistry, University of Cambridge, Cambridge, United Kingdom
⨯
Tuomas P. J. Knowles,

Affiliation Department of Chemistry, University of Cambridge, Cambridge, United Kingdom
⨯
Christopher A. Waudby,

Affiliation Department of Chemistry, University of Cambridge, Cambridge, United Kingdom
⨯
Michele Vendruscolo,

Affiliation Department of Chemistry, University of Cambridge, Cambridge, United Kingdom
⨯
Christopher M. Dobson

* E-mail: cmd44@cam.ac.uk

Affiliation Department of Chemistry, University of Cambridge, Cambridge, United Kingdom
⨯

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Free energy
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Protein folding
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Hydrogen bonding
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Protein interactions
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Amyloid proteins
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Globular proteins
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Protein structure
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Amino acid analysis
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