Systematic Prediction of Pharmacodynamic Drug-Drug Interactions through Protein-Protein-Interaction Network

Jialiang Huang; Chaoqun Niu; Christopher D. Green; Lun Yang; Hongkang Mei; Jing-Dong J. Han

doi:10.1371/journal.pcbi.1002998

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Peer-reviewed

Research Article

Systematic Prediction of Pharmacodynamic Drug-Drug Interactions through Protein-Protein-Interaction Network

Jialiang Huang,

Affiliations Key Laboratory of Computational Biology, Chinese Academy of Sciences-Max Planck Partner Institute for Computational Biology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai, China, Center for Molecular Systems Biology, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing, China, Bioinformatics, Integrated Platform Science, GlaxoSmithKline Research and Development China, Shanghai, China
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Chaoqun Niu,

Affiliations Key Laboratory of Computational Biology, Chinese Academy of Sciences-Max Planck Partner Institute for Computational Biology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai, China, Center for Molecular Systems Biology, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing, China
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Christopher D. Green,

Affiliation Key Laboratory of Computational Biology, Chinese Academy of Sciences-Max Planck Partner Institute for Computational Biology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai, China
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Lun Yang,

Affiliation Systematic Drug Repositioning, Computational Biology, GlaxoSmithKline, Philadelphia, Pennsylvania, United States of America
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Hongkang Mei ,

* E-mail: hongkang.k.mei@gsk.com (HM); jdhan@picb.ac.cn (JDJH)

Affiliation Bioinformatics, Integrated Platform Science, GlaxoSmithKline Research and Development China, Shanghai, China
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Jing-Dong J. Han

* E-mail: hongkang.k.mei@gsk.com (HM); jdhan@picb.ac.cn (JDJH)

Affiliation Key Laboratory of Computational Biology, Chinese Academy of Sciences-Max Planck Partner Institute for Computational Biology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai, China
⨯

Systematic Prediction of Pharmacodynamic Drug-Drug Interactions through Protein-Protein-Interaction Network

Jialiang Huang,
Chaoqun Niu,
Christopher D. Green,
Lun Yang,
Hongkang Mei,
Jing-Dong J. Han

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Published: March 21, 2013
https://doi.org/10.1371/journal.pcbi.1002998

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