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Critical Role of Transient Activity of MT1-MMP for ECM Degradation in Invadopodia

  • Ayako Watanabe,

    Affiliation Division of Mathematical Oncology, The Institute of Medical Science, The University of Tokyo, Minato-ku, Tokyo, Japan

  • Daisuke Hosino,

    Affiliation Division of Cancer Cell Research, The Institute of Medical Science, The University of Tokyo, Minato-ku, Tokyo, Japan

  • Naohiko Koshikawa,

    Affiliation Division of Cancer Cell Research, The Institute of Medical Science, The University of Tokyo, Minato-ku, Tokyo, Japan

  • Motoharu Seiki,

    Affiliations Division of Cancer Cell Research, The Institute of Medical Science, The University of Tokyo, Minato-ku, Tokyo, Japan, JST, CREST, Chiyoda-ku, Tokyo, Japan

  • Takashi Suzuki,

    Affiliations JST, CREST, Chiyoda-ku, Tokyo, Japan, Division of Mathematical Science, Graduate School of Engineering Science, Osaka University, Toyonaka, Osaka, Japan

  • Kazuhisa Ichikawa

    kichi@ims.u-tokyo.ac.jp

    Affiliations Division of Mathematical Oncology, The Institute of Medical Science, The University of Tokyo, Minato-ku, Tokyo, Japan, JST, CREST, Chiyoda-ku, Tokyo, Japan

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