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Research Article

Increasing the Power to Detect Causal Associations by Combining Genotypic and Expression Data in Segregating Populations

  • Jun Zhu equal contributor,

    equal contributor Contributed equally to this work with: Jun Zhu, Matthew C Wiener, Chunsheng Zhang, Arthur Fridman

    Affiliation: Rosetta Inpharmatics, Seattle, Washington, United States of America

    X
  • Matthew C Wiener equal contributor,

    equal contributor Contributed equally to this work with: Jun Zhu, Matthew C Wiener, Chunsheng Zhang, Arthur Fridman

    Affiliation: Department of Applied Computer Science and Mathematics, Merck Research Laboratories, Rahway, New Jersey, United States of America

    X
  • Chunsheng Zhang equal contributor,

    equal contributor Contributed equally to this work with: Jun Zhu, Matthew C Wiener, Chunsheng Zhang, Arthur Fridman

    Affiliation: Rosetta Inpharmatics, Seattle, Washington, United States of America

    X
  • Arthur Fridman equal contributor,

    equal contributor Contributed equally to this work with: Jun Zhu, Matthew C Wiener, Chunsheng Zhang, Arthur Fridman

    Affiliation: Department of Applied Computer Science and Mathematics, Merck Research Laboratories, Rahway, New Jersey, United States of America

    X
  • Eric Minch,

    Affiliation: Department of Applied Computer Science and Mathematics, Merck Research Laboratories, Rahway, New Jersey, United States of America

    X
  • Pek Y Lum,

    Affiliation: Rosetta Inpharmatics, Seattle, Washington, United States of America

    X
  • Jeffrey R Sachs,

    Affiliation: Department of Applied Computer Science and Mathematics, Merck Research Laboratories, Rahway, New Jersey, United States of America

    X
  • Eric E Schadt mail

    To whom correspondence should be addressed. E-mail: Eric_Schadt@merck.com

    Affiliation: Rosetta Inpharmatics, Seattle, Washington, United States of America

    X
  • Published: April 13, 2007
  • DOI: 10.1371/journal.pcbi.0030069

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