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Research Article

Structure-Templated Predictions of Novel Protein Interactions from Sequence Information

  • Doron Betel mail,

    To whom correspondence should be addressed. E-mail: betel@cbio.mskcc.org

    Affiliations: Samuel Lunenfeld Research Institute, Mt. Sinai Hospital, Toronto, Ontario, Canada, Department of Biochemistry, University of Toronto, Toronto, Ontario, Canada

    ¤ Current address: Computational and Systems Biology Center, Memorial Sloan-Kettering Cancer Center, New York, New York, United States of America

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  • Kevin E Breitkreuz,

    Affiliation: Samuel Lunenfeld Research Institute, Mt. Sinai Hospital, Toronto, Ontario, Canada

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  • Ruth Isserlin,

    Affiliations: Samuel Lunenfeld Research Institute, Mt. Sinai Hospital, Toronto, Ontario, Canada, Department of Biochemistry, University of Toronto, Toronto, Ontario, Canada

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  • Danielle Dewar-Darch,

    Affiliation: Samuel Lunenfeld Research Institute, Mt. Sinai Hospital, Toronto, Ontario, Canada

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  • Mike Tyers,

    Affiliations: Samuel Lunenfeld Research Institute, Mt. Sinai Hospital, Toronto, Ontario, Canada, Department of Medical Genetics and Microbiology, University of Toronto, Toronto, Ontario, Canada

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  • Christopher W. V Hogue

    Affiliation: Department of Biochemistry, University of Toronto, Toronto, Ontario, Canada

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  • Published: September 21, 2007
  • DOI: 10.1371/journal.pcbi.0030182

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