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Research Article

Differences in Reactivation of Tuberculosis Induced from Anti-TNF Treatments Are Based on Bioavailability in Granulomatous Tissue

  • Simeone Marino,

    Affiliation: Department of Microbiology and Immunology, University of Michigan Medical School, Ann Arbor, Michigan, United States of America

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  • Dhruv Sud,

    Affiliations: Department of Microbiology and Immunology, University of Michigan Medical School, Ann Arbor, Michigan, United States of America, Department of Biomedical Engineering, College of Engineering, University of Michigan, Ann Arbor, Michigan, United States of America

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  • Hillarie Plessner,

    Affiliation: Department of Molecular Genetics and Biochemistry, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, United States of America

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  • Philana Ling Lin,

    Affiliation: Department of Pediatrics, Division of Pediatric Infectious Disease, Children's Hospital of Pittsburgh, Pittsburgh, Pennsylvania, United States of America

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  • John Chan,

    Affiliations: Department of Medicine, Albert Einstein College of Medicine, New York, New York, United States of America, Department of Microbiology, Albert Einstein College of Medicine, New York, New York, United States of America, Department of Immunology, Albert Einstein College of Medicine, New York, New York, United States of America

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  • JoAnne L Flynn,

    Affiliation: Department of Molecular Genetics and Biochemistry, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, United States of America

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  • Denise E Kirschner mail

    To whom correspondence should be addressed. E-mail: kirschne@umich.edu

    Affiliations: Department of Microbiology and Immunology, University of Michigan Medical School, Ann Arbor, Michigan, United States of America, Department of Medicine, Albert Einstein College of Medicine, New York, New York, United States of America

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  • Published: October 19, 2007
  • DOI: 10.1371/journal.pcbi.0030194

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