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Research Article

Why Do Hubs in the Yeast Protein Interaction Network Tend To Be Essential: Reexamining the Connection between the Network Topology and Essentiality

  • Elena Zotenko,

    Affiliation: Max-Planck Institute for Informatics, Saarbruecken, Germany

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  • Julian Mestre,

    Affiliation: Max-Planck Institute for Informatics, Saarbruecken, Germany

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  • Dianne P. O'Leary,

    Affiliations: Department of Computer Science, University of Maryland, College Park, Maryland, United States of America, Institute for Advanced Computer Studies, University of Maryland, College Park, Maryland, United States of America

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  • Teresa M. Przytycka mail

    przytyck@ncbi.nlm.nih.gov

    Affiliation: National Center of Biotechnology Information, National Library of Medicine, National Institutes of Health, Bethesda, Maryland, United States of America

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  • Published: August 01, 2008
  • DOI: 10.1371/journal.pcbi.1000140

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