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Research Article

Partial Order Optimum Likelihood (POOL): Maximum Likelihood Prediction of Protein Active Site Residues Using 3D Structure and Sequence Properties

  • Wenxu Tong,

    Affiliations: College of Computer and Information Science, Northeastern University, Boston, Massachusetts, United States of America, Institute for Complex Scientific Software, Northeastern University, Boston, Massachusetts, United States of America

    X
  • Ying Wei,

    Affiliations: Institute for Complex Scientific Software, Northeastern University, Boston, Massachusetts, United States of America, Department of Chemistry and Chemical Biology, Northeastern University, Boston, Massachusetts, United States of America

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  • Leonel F. Murga,

    Affiliations: Institute for Complex Scientific Software, Northeastern University, Boston, Massachusetts, United States of America, Department of Chemistry and Chemical Biology, Northeastern University, Boston, Massachusetts, United States of America

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  • Mary Jo Ondrechen mail,

    M.Ondrechen@neu.edu (MO); rjw@ccs.neu.edu (RJW)

    Affiliations: Institute for Complex Scientific Software, Northeastern University, Boston, Massachusetts, United States of America, Department of Chemistry and Chemical Biology, Northeastern University, Boston, Massachusetts, United States of America

    X
  • Ronald J. Williams mail

    M.Ondrechen@neu.edu (MO); rjw@ccs.neu.edu (RJW)

    Affiliations: College of Computer and Information Science, Northeastern University, Boston, Massachusetts, United States of America, Institute for Complex Scientific Software, Northeastern University, Boston, Massachusetts, United States of America

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  • Published: January 16, 2009
  • DOI: 10.1371/journal.pcbi.1000266

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