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Research Article

A Variant of TNFR2-Fc Fusion Protein Exhibits Improved Efficacy in Treating Experimental Rheumatoid Arthritis

  • Tong Yang equal contributor,

    equal contributor Contributed equally to this work with: Tong Yang, Zheng Wang

    Affiliation: Department of Genetic Engineering Development, Shanghai Fudan-Zhangjiang Bio-pharmaceutical Co., Ltd., Shanghai, China

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  • Zheng Wang equal contributor,

    equal contributor Contributed equally to this work with: Tong Yang, Zheng Wang

    Affiliation: Department of Genetic Engineering Development, Shanghai Fudan-Zhangjiang Bio-pharmaceutical Co., Ltd., Shanghai, China

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  • Fang Wu,

    Affiliation: Department of Genetic Engineering Development, Shanghai Fudan-Zhangjiang Bio-pharmaceutical Co., Ltd., Shanghai, China

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  • Jingwei Tan,

    Affiliation: Department of Genetic Engineering Development, Shanghai Fudan-Zhangjiang Bio-pharmaceutical Co., Ltd., Shanghai, China

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  • Yijun Shen,

    Affiliation: Department of Genetic Engineering Development, Shanghai Fudan-Zhangjiang Bio-pharmaceutical Co., Ltd., Shanghai, China

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  • Erguang Li,

    Affiliation: School of Medicine, Nanjing University, Nanjing, China

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  • Jingzhi Dai,

    Affiliation: Shanghai Institute of Pharmaceutical Industry, Shanghai, China

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  • Ronghai Shen,

    Affiliation: Shanghai Institute of Pharmaceutical Industry, Shanghai, China

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  • Gang Li,

    Affiliation: Department of Genetic Engineering Development, Shanghai Fudan-Zhangjiang Bio-pharmaceutical Co., Ltd., Shanghai, China

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  • Jinsong Wu,

    Affiliation: Department of Genetic Engineering Development, Shanghai Fudan-Zhangjiang Bio-pharmaceutical Co., Ltd., Shanghai, China

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  • Luochun Wang,

    Affiliation: Department of Genetic Engineering Development, Shanghai Fudan-Zhangjiang Bio-pharmaceutical Co., Ltd., Shanghai, China

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  • Haibo Wang,

    Affiliation: Department of Genetic Engineering Development, Shanghai Fudan-Zhangjiang Bio-pharmaceutical Co., Ltd., Shanghai, China

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  • Yanjun Liu mail

    yjliu@fd-zj.com

    Affiliations: Department of Genetic Engineering Development, Shanghai Fudan-Zhangjiang Bio-pharmaceutical Co., Ltd., Shanghai, China, Taizhou Fudan-Zhangjiang Bio-pharmaceutical Co., Ltd., Taizhou City, Jiangsu Province, China

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  • Published: February 05, 2010
  • DOI: 10.1371/journal.pcbi.1000669

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