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Research Article

Intrinsically Disordered Regions May Lower the Hydration Free Energy in Proteins: A Case Study of Nudix Hydrolase in the Bacterium Deinococcus radiodurans

  • Omar Awile,

    Affiliations: Mediterranean Institute for Life Sciences, Split, Croatia, Institute of Theoretical Computer Science and Swiss Institute of Bioinformatics, Zürich, Switzerland

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  • Anita Krisko,

    Affiliation: Faculte de Medecine Paris Descartes, INSERM U1001, Paris, France

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  • Ivo F. Sbalzarini,

    Affiliations: Mediterranean Institute for Life Sciences, Split, Croatia, Institute of Theoretical Computer Science and Swiss Institute of Bioinformatics, Zürich, Switzerland

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  • Bojan Zagrovic mail

    bojan.zagrovic@univie.ac.at

    Affiliations: Mediterranean Institute for Life Sciences, Split, Croatia, Department of Physics, University of Split, Split, Croatia, University of Vienna, Department of Structural & Computational Biology, Max F. Perutz Laboratories, Vienna, Austria

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  • Published: July 15, 2010
  • DOI: 10.1371/journal.pcbi.1000854

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