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Research Article

Genetic Signatures in the Envelope Glycoproteins of HIV-1 that Associate with Broadly Neutralizing Antibodies

  • S. Gnanakaran,

    Affiliation: Theoretical Biology and Biophysics, Los Alamos National Laboratory, Los Alamos, New Mexico, United States of America

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  • Marcus G. Daniels,

    Affiliation: Theoretical Biology and Biophysics, Los Alamos National Laboratory, Los Alamos, New Mexico, United States of America

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  • Tanmoy Bhattacharya,

    Affiliations: Theoretical Biology and Biophysics, Los Alamos National Laboratory, Los Alamos, New Mexico, United States of America, Santa Fe Institute, Santa Fe, New Mexico, United States of America

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  • Alan S. Lapedes,

    Affiliation: Theoretical Biology and Biophysics, Los Alamos National Laboratory, Los Alamos, New Mexico, United States of America

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  • Anurag Sethi,

    Affiliations: Theoretical Biology and Biophysics, Los Alamos National Laboratory, Los Alamos, New Mexico, United States of America, Center for Nonlinear Studies, Los Alamos National Laboratory, Los Alamos, New Mexico, United States of America

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  • Ming Li,

    Affiliation: Department of Surgery, Duke University Medical Center, Durham, North Carolina, United States of America

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  • Haili Tang,

    Affiliation: Department of Surgery, Duke University Medical Center, Durham, North Carolina, United States of America

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  • Kelli Greene,

    Affiliation: Department of Surgery, Duke University Medical Center, Durham, North Carolina, United States of America

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  • Hongmei Gao,

    Affiliation: Department of Surgery, Duke University Medical Center, Durham, North Carolina, United States of America

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  • Barton F. Haynes,

    Affiliation: Department of Medicine, Duke University Medical Center, Durham, North Carolina, United States of America

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  • Myron S. Cohen,

    Affiliation: Department of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America

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  • George M. Shaw,

    Affiliations: Department of Medicine, University of Alabama at Birmingham, Birmingham, Alabama, United States of America, Department of Microbiology, University of Alabama at Birmingham, Birmingham, Alabama, United States of America

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  • Michael S. Seaman,

    Affiliation: Division of Viral Pathogenesis, Beth Israel Deaconess Medical Center, Boston, Massachusetts, United States of America

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  • Amit Kumar,

    Affiliation: Department of Medicine, Duke University Medical Center, Durham, North Carolina, United States of America

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  • Feng Gao,

    Affiliation: Department of Medicine, Duke University Medical Center, Durham, North Carolina, United States of America

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  • David C. Montefiori,

    Affiliation: Department of Surgery, Duke University Medical Center, Durham, North Carolina, United States of America

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  • Bette Korber mail

    btk@lanl.gov

    Affiliations: Theoretical Biology and Biophysics, Los Alamos National Laboratory, Los Alamos, New Mexico, United States of America, Santa Fe Institute, Santa Fe, New Mexico, United States of America

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  • Published: October 07, 2010
  • DOI: 10.1371/journal.pcbi.1000955

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