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Research Article

deFuse: An Algorithm for Gene Fusion Discovery in Tumor RNA-Seq Data

  • Andrew McPherson,

    Affiliations: Centre for Translational and Applied Genomics, BC Cancer Agency, Vancouver, British Columbia, Canada, School of Computing Science, Simon Fraser University, Burnaby, British Columbia, Canada

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  • Fereydoun Hormozdiari,

    Affiliation: School of Computing Science, Simon Fraser University, Burnaby, British Columbia, Canada

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  • Abdalnasser Zayed,

    Affiliation: Centre for Translational and Applied Genomics, BC Cancer Agency, Vancouver, British Columbia, Canada

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  • Ryan Giuliany,

    Affiliation: Centre for Translational and Applied Genomics, BC Cancer Agency, Vancouver, British Columbia, Canada

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  • Gavin Ha,

    Affiliation: Centre for Translational and Applied Genomics, BC Cancer Agency, Vancouver, British Columbia, Canada

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  • Mark G. F. Sun,

    Affiliation: Centre for Translational and Applied Genomics, BC Cancer Agency, Vancouver, British Columbia, Canada

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  • Malachi Griffith,

    Affiliation: Canada's Michael Smith Genome Sciences Centre, BC Cancer Agency, Vancouver, British Columbia, Canada

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  • Alireza Heravi Moussavi,

    Affiliation: Centre for Translational and Applied Genomics, BC Cancer Agency, Vancouver, British Columbia, Canada

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  • Janine Senz,

    Affiliation: Centre for Translational and Applied Genomics, BC Cancer Agency, Vancouver, British Columbia, Canada

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  • Nataliya Melnyk,

    Affiliation: Centre for Translational and Applied Genomics, BC Cancer Agency, Vancouver, British Columbia, Canada

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  • Marina Pacheco,

    Affiliation: Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, Canada

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  • Marco A. Marra,

    Affiliation: Canada's Michael Smith Genome Sciences Centre, BC Cancer Agency, Vancouver, British Columbia, Canada

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  • Martin Hirst,

    Affiliation: Canada's Michael Smith Genome Sciences Centre, BC Cancer Agency, Vancouver, British Columbia, Canada

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  • Torsten O. Nielsen,

    Affiliation: Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, Canada

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  • S. Cenk Sahinalp,

    Affiliation: School of Computing Science, Simon Fraser University, Burnaby, British Columbia, Canada

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  • David Huntsman,

    Affiliations: Centre for Translational and Applied Genomics, BC Cancer Agency, Vancouver, British Columbia, Canada, Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, Canada

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  • Sohrab P. Shah mail

    sshah@bccrc.ca

    Affiliations: Centre for Translational and Applied Genomics, BC Cancer Agency, Vancouver, British Columbia, Canada, Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, Canada, Department of Molecular Oncology, BC Cancer Agency, Vancouver, British Columbia, Canada

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  • Published: May 19, 2011
  • DOI: 10.1371/journal.pcbi.1001138

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