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Research Article

Quantitative Epistasis Analysis and Pathway Inference from Genetic Interaction Data

  • Hilary Phenix,

    Affiliations: Ottawa Institute of Systems Biology, University of Ottawa, Ottawa, Ontario, Canada, Department of Cellular and Molecular Medicine, University of Ottawa, Ottawa, Ontario, Canada

    X
  • Katy Morin,

    Affiliations: Ottawa Institute of Systems Biology, University of Ottawa, Ottawa, Ontario, Canada, Department of Biochemistry, Immunology and Microbiology, University of Ottawa, Ottawa, Ontario, Canada

    X
  • Cory Batenchuk,

    Affiliations: Ottawa Institute of Systems Biology, University of Ottawa, Ottawa, Ontario, Canada, Department of Cellular and Molecular Medicine, University of Ottawa, Ottawa, Ontario, Canada

    X
  • Jacob Parker,

    Affiliations: Ottawa Hospital Research Institute, Ottawa, Ontario, Canada, Department of Applied Mathematics, University of Waterloo, Waterloo, Ontario, Canada

    X
  • Vida Abedi,

    Affiliations: Ottawa Institute of Systems Biology, University of Ottawa, Ottawa, Ontario, Canada, Department of Cellular and Molecular Medicine, University of Ottawa, Ottawa, Ontario, Canada

    X
  • Liu Yang,

    Affiliations: Ottawa Institute of Systems Biology, University of Ottawa, Ottawa, Ontario, Canada, Department of Cellular and Molecular Medicine, University of Ottawa, Ottawa, Ontario, Canada, Department of Applied Mathematics, University of Waterloo, Waterloo, Ontario, Canada

    X
  • Lioudmila Tepliakova,

    Affiliations: Ottawa Institute of Systems Biology, University of Ottawa, Ottawa, Ontario, Canada, Department of Cellular and Molecular Medicine, University of Ottawa, Ottawa, Ontario, Canada

    X
  • Theodore J. Perkins,

    Affiliations: Department of Biochemistry, Immunology and Microbiology, University of Ottawa, Ottawa, Ontario, Canada, Ottawa Hospital Research Institute, Ottawa, Ontario, Canada

    X
  • Mads Kærn mail

    mkaern@uottawa.ca

    Affiliations: Ottawa Institute of Systems Biology, University of Ottawa, Ottawa, Ontario, Canada, Department of Cellular and Molecular Medicine, University of Ottawa, Ottawa, Ontario, Canada, Department of Physics, University of Ottawa, Ottawa, Ontario, Canada

    X
  • Published: May 12, 2011
  • DOI: 10.1371/journal.pcbi.1002048

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