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Research Article

Protein Scaffolds Can Enhance the Bistability of Multisite Phosphorylation Systems

  • Carlo Chan,

    Affiliation: Department of Mathematics, Center for Mathematical and Complex Biological Systems, Center for Complex Biological Systems, University of California, Irvine, California, United States of America

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  • Xinfeng Liu,

    Affiliation: Department of Mathematics, University of South Carolina, Columbia, South Carolina, United States of America

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  • Liming Wang,

    Affiliation: Department of Mathematics, California State University, Los Angeles, California, United States of America

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  • Lee Bardwell,

    Affiliation: Department of Developmental and Cell Biology, School of Biological Sciences, University of California, Irvine, California, United States of America

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  • Qing Nie equal contributor,

    equal contributor Contributed equally to this work with: Qing Nie, Germán Enciso

    Affiliation: Department of Mathematics, Center for Mathematical and Complex Biological Systems, Center for Complex Biological Systems, University of California, Irvine, California, United States of America

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  • Germán Enciso equal contributor mail

    equal contributor Contributed equally to this work with: Qing Nie, Germán Enciso

    enciso@uci.edu

    Affiliation: Department of Mathematics, Center for Mathematical and Complex Biological Systems, Center for Complex Biological Systems, University of California, Irvine, California, United States of America

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  • Published: June 21, 2012
  • DOI: 10.1371/journal.pcbi.1002551

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