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Research Article

A Nonlinear Dynamic Approach Reveals a Long-Term Stroke Effect on Cerebral Blood Flow Regulation at Multiple Time Scales

  • Kun Hu mail,

    khu@bics.bwh.harvard.edu (KH); mzlo@ncu.edu.tw (MTL)

    Affiliations: Division of Sleep Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, United States of America, Division of Gerontology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, United States of America, Center for Dynamical Biomarkers and Translational Medicine, National Central University, Chungli, Taiwan

    X
  • Men-Tzung Lo mail,

    khu@bics.bwh.harvard.edu (KH); mzlo@ncu.edu.tw (MTL)

    Affiliations: Division of Gerontology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, United States of America, Center for Dynamical Biomarkers and Translational Medicine, National Central University, Chungli, Taiwan, Division of Interdisciplinary Medicine & Biotechnology and Margret & H.A. Rey Institute for Nonlinear Dynamics in Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, United States of America, Research Center for Adaptive Data Analysis, National Central University, Chungli, Taiwan

    X
  • Chung-Kang Peng,

    Affiliations: Center for Dynamical Biomarkers and Translational Medicine, National Central University, Chungli, Taiwan, Division of Interdisciplinary Medicine & Biotechnology and Margret & H.A. Rey Institute for Nonlinear Dynamics in Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, United States of America

    X
  • Yanhui Liu,

    Affiliation: DynaDx Corporation, Mountain View, California, United States of America

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  • Vera Novak

    Affiliations: Division of Gerontology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, United States of America, Center for Dynamical Biomarkers and Translational Medicine, National Central University, Chungli, Taiwan

    X
  • Published: July 12, 2012
  • DOI: 10.1371/journal.pcbi.1002601

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