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Research Article

Tissue-Specific Functional Networks for Prioritizing Phenotype and Disease Genes

  • Yuanfang Guan,

    Affiliations: Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, Michigan, United States of America, Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan, United States of America

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  • Dmitriy Gorenshteyn,

    Affiliations: Lewis-Sigler Institute for Integrative Genomics, Princeton University, Princeton, New Jersey, United States of America, Department of Molecular Biology, Princeton University, Princeton, New Jersey, United States of America

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  • Margit Burmeister,

    Affiliations: Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, Michigan, United States of America, Molecular & Behavioral Neuroscience Institution, Department of Psychiatry, and Department of Human Genetics, University of Michigan, Ann Arbor, Michigan, United States of America

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  • Aaron K. Wong,

    Affiliation: Lewis-Sigler Institute for Integrative Genomics, Princeton University, Princeton, New Jersey, United States of America

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  • John C. Schimenti,

    Affiliation: Department of Biomedical Sciences, College of Veterinary Medicine, Cornell University, Ithaca, New York, United States of America

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  • Mary Ann Handel,

    Affiliation: The Jackson Laboratory, Bar Harbor, Maine, United States of America

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  • Carol J. Bult,

    Affiliation: The Jackson Laboratory, Bar Harbor, Maine, United States of America

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  • Matthew A. Hibbs mail,

    matt.hibbs@jax.org (MAH); ogt@genomics.princeton.edu (OGT)

    Affiliations: The Jackson Laboratory, Bar Harbor, Maine, United States of America, Trinity University, Computer Science Department, San Antonio, Texas, United States of America

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  • Olga G. Troyanskaya mail

    matt.hibbs@jax.org (MAH); ogt@genomics.princeton.edu (OGT)

    Affiliations: Lewis-Sigler Institute for Integrative Genomics, Princeton University, Princeton, New Jersey, United States of America, Department of Computer Science, Princeton University, Princeton, New Jersey, United States of America

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  • Published: September 27, 2012
  • DOI: 10.1371/journal.pcbi.1002694

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