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Research Article

Coupling between Catalytic Loop Motions and Enzyme Global Dynamics

  • Zeynep Kurkcuoglu,

    Affiliation: Department of Chemical Engineering and Polymer Research Center, Bogazici University, Bebek, Istanbul, Turkey

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  • Ahmet Bakan,

    Affiliation: Department of Computational and Systems Biology, and Clinical & Translational Science Institute, School of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America

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  • Duygu Kocaman,

    Affiliation: Department of Chemical Engineering and Polymer Research Center, Bogazici University, Bebek, Istanbul, Turkey

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  • Ivet Bahar mail,

    bahar@pitt.edu (IB); pemra@prc.boun.edu.tr (PD)

    Affiliation: Department of Computational and Systems Biology, and Clinical & Translational Science Institute, School of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America

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  • Pemra Doruker mail

    bahar@pitt.edu (IB); pemra@prc.boun.edu.tr (PD)

    Affiliation: Department of Chemical Engineering and Polymer Research Center, Bogazici University, Bebek, Istanbul, Turkey

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  • Published: September 27, 2012
  • DOI: 10.1371/journal.pcbi.1002705

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