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Research Article

Modeling Bi-modality Improves Characterization of Cell Cycle on Gene Expression in Single Cells

  • Andrew McDavid equal contributor,

    equal contributor Contributed equally to this work with: Andrew McDavid, Lucas Dennis

    Affiliations: Department of Statistics, University of Washington, Seattle, Washington, United States of America, Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center, Seattle, Washington, United States of America

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  • Lucas Dennis equal contributor,

    equal contributor Contributed equally to this work with: Andrew McDavid, Lucas Dennis

    Affiliation: NanoString Technologies, Seattle, Washington, United States of America

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  • Patrick Danaher,

    Affiliation: NanoString Technologies, Seattle, Washington, United States of America

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  • Greg Finak,

    Affiliation: Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center, Seattle, Washington, United States of America

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  • Michael Krouse,

    Affiliation: NanoString Technologies, Seattle, Washington, United States of America

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  • Alice Wang,

    Affiliation: BD Biosciences, San Jose, California, United States of America

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  • Philippa Webster,

    Affiliation: NanoString Technologies, Seattle, Washington, United States of America

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  • Joseph Beechem,

    Affiliation: NanoString Technologies, Seattle, Washington, United States of America

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  • Raphael Gottardo mail

    raph@rglab.org

    Affiliations: Department of Statistics, University of Washington, Seattle, Washington, United States of America, Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center, Seattle, Washington, United States of America

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  • Published: July 17, 2014
  • DOI: 10.1371/journal.pcbi.1003696

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